Organic Acids Test (OAT)

What are Organic Acids?

I give a bit more detail below about the Organic Acids Test (OAT) – which is a simple urine test that you can do at home but which gives a huge amount of information about the current state of your health.

The Organic Acids Test (OAT) examines metabolites (chemical substances produced by your metabolism) that are coming out with, and in, your urine. These metabolites can give clues about the efficiency (or lack of) of your internal cellular processes, as well as gut microbes. It gives clues if we have a blockage, nutritional insufficiencies, and/or bacterial overgrowth.

Organic acids are the by-products of cellular metabolism, i.e. your cellular metabolism is made up of certain steps of certain biochemical reactions and pathways based on your body’s needs. So if my body needs energy, for example, certain metabolic reactions down a pathway occur to create that energy. Or if I need to break down the food I eat, there are certain metabolic chemical reactions down that pathway to do so. And in creating those different metabolic pathways, certain acids are used and/or produced. They range from acetic acid, butyric acid, oxalic acid, lactic acid, malic acid, uric acid, citric acid and more.

But sometimes, those metabolic pathways don’t work the way they should! Because of a nutrient deficiency or an inherited block, they go down DIFFERENT pathways in trying to create the same end result, but which can be inefficient or problematic. And what comes out in your urine via the organic acids reveals so much of what can be going on inside you that’s inefficient or needs help. This can often highlight the cause of a health problem.

What does the Organic Acid Test reveal?

  • Vitamin and mineral insufficiencies
  • Amino acid insufficiencies
  • Oxidative damage and antioxidant sufficiency
  • Indicators to assess detoxification sufficiency
  • The best functional markers of B-complex deficiency
  • Neurotransmitter metabolites to assess central nervous system (CNS) function
  • Mitochondrial energy production assessment via citric acid cycle components
  • Methylation sufficiency status
  • Lipoic acid and CoQ10 sufficiency
  • Specific dysbiosis markers for bacterial and yeast overgrowth


What’s on offer

There are a couple of companies which offer organic acids testing (OAT) – namely Great Plains Laboratory and Genova Diagnostics.  I use both.